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Kevin T. Conroy was named President and Chief Executive Officer of Exact Sciences in April 2009. He also serves as a Director. In December 2005, he was appointed President and Chief Executive of Third Wave, and served in that position until the company's acquisition by Hologic in July 2008. He joined Third Wave in July 2004 and served as the company's general counsel until December 2005. Prior to joining Third Wave, Conroy served as Intellectual Property counsel at GE Healthcare. Before joining GE Healthcare, Conroy was Chief Operating Officer of two early stage, venture-backed technology companies in Northern California. Prior to those positions, he was an Intellectual Property litigator at two Chicago law firms: McDermott Will & Emery; and Pattishall, McAuliffe, Newbury, Hilliard and Geraldson, where he was a partner. He earned a Bachelor of Science degree in electrical engineering from Michigan State University, as well as a law degree from the University of Michigan Law School.

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Graham P. Lidgard, Ph.D., was appointed Chief Science Officer of Exact Sciences in August 2009. Dr. Lidgard led the research and development organization at Gen-Probe Inc. that developed that company's Procleix blood screening products and Aptima sexually transmitted disease products. Dr. Lidgard also created and led the system development group at Gen-Probe that developed its fully automated Tigris system. Prior to joining Gen-Probe, Dr. Lidgard was co-founder and Vice President of product development of Matritech Inc., a Cambridge, Massachusetts-based developer of diagnostic products for the early detection of bladder cancer. Before he co-founded Matritech, Dr. Lidgard held senior positions at Ciba Corning Diagnostics Corp.'s worldwide diagnostics group. While at Ciba Corning, he was involved in the development of more than 70 510(k)-cleared products. He led the program for the development of the magnetic particle chemiluminescent technology that became the ACS:180 and Centaur systems. Dr. Lidgard joins Exact Sciences from Nanogen Inc., where he was Senior Vice President of research and development. Dr. Lidgard earned a Bachelor's degree with honors and a Doctorate in biological chemistry from the University of Manchester in England.
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Maneesh K. Arora has served as Exact’s chief operating officer since February 2012 and as a senior vice president since April 2009, when he joined the company. Mr. Arora also served as the company’s chief financial officer from April 2009 to August 2013. Prior to joining Exact, Mr. Arora worked for Third Wave Technologies Inc., a molecular diagnostics company, from 2003 until its acquisition by Hologic Inc. in July 2008. During his time at Third Wave, Mr. Arora was responsible for business strategy and commercial operations before being promoted to chief financial officer in January 2006. Mr. Arora earned a bachelor’s degree in economics from the University of Chicago and an MBA from the Kellogg Graduate School of Management at Northwestern University